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Article

CTLA-4, CD28, and ICOS gene polymorphism associations with non-small-cell lung cancer.

Human immunology - 1 Oct 2011

Karabon Lidia, Pawlak Edyta, Tomkiewicz Anna, Jedynak Anna, Passowicz-Muszynska Ewa, Zajda Katarzyna, Jonkisz Anna, Jankowska Renata, Krzakowski Maciej, Frydecka Irena

Abstract excerpt

Polymorphisms in genes encoding CD28, ICOS, and CTLA-4 were demonstrated to be associated with susceptibility to malignancies. To the best of our knowledge, no study on this association has been performed in a Caucasian population for non-small-cell lung cancer (NSCLC). In the present work, we investigated the polymorphisms CTLA-4c.49A>G (rs231775), CTLA-4g.319C>T (rs5742909), CTLA-4g.*642AT(8_33),...

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PMID: 21669243
DOI: 10.1016/j.humimm.2011.05.010

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ICOS

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