Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV Gag.

Virology - 10 Nov 2005

Zhao Jun, Voltan Rebecca, Peng Bo, Davis-Warren Alberta, Kalyanaraman V S, Alvord W Gregory, Aldrich Kris, Bernasconi Daniela, Buttò Stefano, Cafaro Aurelio, Ensoli Barbara, Robert-Guroff Marjorie

Abstract excerpt

Among candidate antigens for human immunodeficiency virus (HIV) prophylactic vaccines, the regulatory protein Tat is a critical early target, but has a potential for immune suppression. Adenovirus (Ad) recombinants encoding wild-type HIV Tat (Tat-wt) and a transdominant negative mutant HIV Tat (Tat22) were constructed and administered to mice separately or together with Ad-SIVgag. Immunogenicity and effects on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS Vaccines
Share to Gene Products, gag

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, tat

Share to Genes, gag

Share to Genes, tat

Share to HIV Antibodies

Share to tat Gene Products, Human Immunodeficiency Virus

Share to Vaccines, Synthetic

Source

Identifiers

PMID: 16109434
DOI: 10.1016/j.virol.2005.07.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV Gag.PMID 16109434Read ↗

Enhancement of humoral immunity to SIVenv following simultaneous inoculation of mice by three recombinant adenoviruses encoding SIVenv/poliovirus chimeras, Tat and Rev.Semantic proximity Read ↗

Magnitude and Phenotype of Cellular Immune Responses Elicited by Recombinant Adenovirus Vectors and Heterologous Prime-Boost Regimens in Rhesus MonkeysSemantic proximity Read ↗

Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell ImmunogenicitySemantic proximity Read ↗

HIV-1 Tat protein as a potential AIDS vaccine.Semantic proximity Read ↗

Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals.Semantic proximity Read ↗

A Simian Replication-Defective Adenoviral Recombinant Vaccine to HIV-1 GagSemantic proximity Read ↗

Design and characterization of an HIV-1 Tat mutant: inactivation of viral and cellular functions but not antigenicity.Semantic proximity Read ↗

Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 ImmunitySemantic proximity Read ↗

DNA gag/adenovirus type 5 (Ad5) gag and Ad5 gag/Ad5 gag vaccines induce distinct T-cell response profiles.Semantic proximity Read ↗

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 <sup>+</sup> T cellsSemantic proximity Read ↗

Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected AdultsSemantic proximity Read ↗

Characterization of HIV-1 Tat proteins mutated in the transactivation domain for prophylactic and therapeutic application.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.