Article
Characterization of HIV-1 Tat proteins mutated in the transactivation domain for prophylactic and therapeutic application.
Vaccine - 14 May 2001
Betti M, Voltan R, Marchisio M, Mantovani I, Boarini C, Nappi F, Ensoli B, Caputo A
Abstract excerpt
Previous work from our group showed that genetic immunization of mice with HIV-1 tat genes (tat22 and tat22/37), encoding Tat proteins mutated in the transactivation domain and lacking Tat-transactivating activity, evoke an immune response to wild-type Tat, both humoral and cellular. In the prese...
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