Article
Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates.
Pediatric diabetes - 1 Sept 2005
Emery Lisa M, Babu Sunanda, Bugawan Teodorica L, Norris Jill M, Erlich Henry A, Eisenbarth George S, Rewers Marian
Abstract excerpt
OBJECTIVE: Certain human leukocyte antigen (HLA)-DR,DQ genotypes have been associated with type 1 diabetes mellitus (T1DM) risk, although it is unknown whether the association is due to alleles, haplotypes, genotypes, the formation of heterodimers, or all of the above. To characterize the role of the HLA-DR,DQ genotype and ethnicity on the onset age of T1DM, we analyzed these factors in patients with T1DM and the...
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