Article
Structural insights into the substrate-binding mechanism for a novel chitosanase.
The Biochemical journal - 15 Jul 2014
Lyu Qianqian, Wang Song, Xu Wenhua, Han Baoqin, Liu Wanshun, Jones David N M, Liu Weizhi
Abstract excerpt
Chitosanase is able to specifically cleave β-1,4-glycosidic bond linkages in chitosan to produce a chito-oligomer product, which has found a variety of applications in many areas, including functional food and cancer therapy. Although several structures for chitosanase have been determined, the substrate-binding mechanism for this enzyme has not been fully elucidated because of the lack of a high-resolution...
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