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Article

A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity.

Genes, brain, and behavior - 1 Nov 2021

Goldberg Lisa R, Yao Emily J, Kelliher Julia C, Reed Eric R, Wu Cox Jiayi, Parks Cory, Kirkpatrick Stacey L, Beierle Jacob A, Chen Melanie M, Johnson William E, Homanics Gregg E, Williams Robert W, Bryant Camron D, Mulligan Megan K

Abstract excerpt

Psychostimulant (methamphetamine, cocaine) use disorders have a genetic component that remains mostly unknown. We conducted genome-wide quantitative trait locus (QTL) analysis of methamphetamine stimulant sensitivity. To facilitate gene identification, we employed a Reduced Complexity Cross between closely related C57BL/6 mouse substrains and examined maximum speed and distance traveled over 30 min following...

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Share to Amphetamine-Related Disorders
Share to Central Nervous System Stimulants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methamphetamine

Share to Mice, Inbred C57BL

Share to Quantitative Trait, Heritable

Share to Quantitative Trait Loci

Share to Receptors, GABA-A

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Identifiers

PMID: 34677900
DOI: 10.1111/gbb.12774
PMCID: PMC9083095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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