Article
Influence of fibrillin-1 genotype on the aortic stiffness in men.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Sept 2005
Powell J T, Turner R J, Sian M, Debasso R, Länne T
Abstract excerpt
Aortic stiffness is a predictor of cardiovascular mortality. The mechanical properties of the arterial wall depend on the connective tissue framework, with variation in fibrillin-1 and collagen I genes being associated with aortic stiffness and/or pulse pressure elevation. The aim of this study was to investigate whether variation in fibrillin-1 genotype was associated with aortic stiffness in men. The mechanical...
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