Article
No differences in FBN1 genotype between men with and without abdominal aortic aneurysm.
BMC cardiovascular disorders - 20 Jan 2023
Åström Malm Ida, De Basso Rachel, Blomstrand Peter
Abstract excerpt
BACKGROUND: Abdominal aortic aneurysm (AAA) is an aortic enlargement in which the transverse diameter reaches at least 30 mm. Certain risk factors, such as age, male gender, and smoking, are well known; however, less is known about the genetic factors involved. Fibrillin-1 (FBN1) is a protein that coordinates the deposition of elastin fibres in the extracellular matrix and is therefore likely to affect the...
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