Article

Large artery stiffness : genes and pathways

2018-01-01

Abstract excerpt

Aortic stiffness underlies systolic hypertension, promotes heart failure and is associated with increased cardiovascular morbidity and mortality. It is regarded as a primary driver of left ventricular hypertrophy and aortic aneurysms and is linked to the pathogenesis of cognitive impairment, stroke and renal failure. Like most cardiovascular traits, aortic stiffness is a complex trait and is moderately heritable,...

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Literature Corpus work: 78303eba-6bfb-5b39-b823-2725eb1269b0
DOI: 10.17863/cam.25210

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