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Article

Increased carotid plaque burden in men with the fibrillin-1 2/3 genotype.

Clinical and experimental pharmacology & physiology - 1 Sept 2014

De Basso Rachel, Hedblad Bo, Carlson Joyce, Persson Margaretha, Ostling Gerd, Länne Toste

Abstract excerpt

Fibrillin-1 (FBN1) is an important constituent of the vascular wall and earlier studies have indicated an effect of the FBN1 2/3 genotype on blood pressure as well as aortic stiffness in men. The aim of the present study was to determine whether the FBN1 2/3 genotype was associated with the presence of carotid plaque and incident cardiovascular morbidity and mortality in middle-aged subjects. The FBN1 genotype...

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Source

Identifiers

PMID: 24837032
DOI: 10.1111/1440-1681.12259

Genes

FBN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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