Article
Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2005
Tang Jianming, Shao Wenshuo, Dorak M Tevfik, Li Yufeng, Miike Rei, Lobashevsky Elena, Wiencke John K, Wrensch Margaret, Kaslow Richard A, Cobbs Charles S
Abstract excerpt
Associations of genetic factors with malignant gliomas have been modest. We examined the relationships of human leukocyte antigen (HLA) and related polymorphisms to glioblastoma multiforme in adult Caucasians (non-Hispanic Whites) from the San Francisco Bay area. For 155 glioblastoma multiforme patients and 157 control subjects closely matched by ethnicity, age, and gender, PCR-based techniques resolved alleles...
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