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Article

Activities of human papillomavirus 16 E6 natural variants in human keratinocytes.

Journal of medical virology - 1 Nov 2007

Asadurian Yulia, Kurilin Helena, Lichtig Hava, Jackman Anna, Gonen Pinhas, Tommasino Massimo, Zehbe Ingeborg, Sherman Levana

Abstract excerpt

Genetic variations in the E6 oncogene have been associated with different risk for cancer progression. In the present study, the functional significance of human papillomavirus (HPV) polymorphism in the E6 oncogene was investigated. Ten HPV16 E6 variants containing amino acid substitutions in the N-terminal region of E6 were evaluated for different biological and biochemical activities in human keratinocytes, the...

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PMID: 17854024
DOI: 10.1002/jmv.20978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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