Article
Analysis of polymorphisms in the promoter region of interleukin-1beta by restriction fragment length polymorphism-PCR.
Chinese journal of traumatology = Zhonghua chuang shang za zhi - 1 Oct 2004
Wen Ai-Qing, Wang Jun, Feng Kai, Zhu Pei-Fang, Jiang Jian-Xin
Abstract excerpt
OBJECTIVE: To investigate the frequencies of -1470, -511 and -31 single nucleotide polymorphisms (SNPs) in the promoter of IL-1beta and its haplotype constitution in Chongqing population. METHODS: One hundred and twelve healthy Chongqing people were enrolled in this study. Polymorphisms at -1470 (G to C), -511 (T to C) and -31 (C to T) of IL-1beta were genotyped with the method of restriction fragment length...
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