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Article

Integrating epidemiology and genetic association: the challenge of gene-environment interaction.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Aug 2005

Kraft Peter, Hunter David

Abstract excerpt

Recent advances in human genomics have made it possible to better understand the genetic basis of disease. In addition, genetic association studies can also elucidate the mechanisms by which "non-genetic" exogenous and endogenous exposures influence the risk of disease. This is true both of studies that assess the marginal effect of a single gene and studies that look at the joint effect of genes and...

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Identifiers

PMID: 16096111
DOI: 10.1098/rstb.2005.1692
PMCID: PMC1569522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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