Article
Recombination hotspots as a point process.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Aug 2005
De Iorio Maria, de Silva Eric, Stumpf Michael P H
Abstract excerpt
The variation of the recombination rate along chromosomal DNA is one of the important determinants of the patterns of linkage disequilibrium. A number of inferential methods have been developed which estimate the recombination rate and its variation from population genetic data. The majority of these methods are based on modelling the genealogical process underlying a sample of DNA sequences and thus explicitly...
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