Article
The genetics of human drug response.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Aug 2005
Goldstein David B
Abstract excerpt
The genetics of variable drug response appears to be a more tractable complex trait than common disease predisposition. This has implications for prioritizing research and for experimental design, and in particular argues for extensive use of candidate gene based approaches in pharmacogenetic association studies. Eventually, when whole genome scanning becomes feasible, it may be appropriate to consider weighting...
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