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Article

Personalized medicine: Genetic risk prediction of drug response.

Pharmacology & therapeutics - 1 Jul 2017

Zhang Ge, Nebert Daniel W

Abstract excerpt

Pharmacogenomics (PGx), a substantial component of "personalized medicine", seeks to understand each individual's genetic composition to optimize drug therapy -- maximizing beneficial drug response, while minimizing adverse drug reactions (ADRs). Drug responses are highly variable because innumerable factors contribute to ultimate phenotypic outcomes. Recent genome-wide PGx studies have provided some insight into...

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Identifiers

PMID: 28213088
DOI: 10.1016/j.pharmthera.2017.02.036
PMCID: PMC5653378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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