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Article

Eight base changes are sufficient to convert a leucine-inserting tRNA into a serine-inserting tRNA.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 1992

Normanly J, Ollick T, Abelson J

Abstract excerpt

Each aminoacyl-tRNA synthetase must functionally distinguish its cognate tRNAs from all others. We have determined the minimum number of changes required to transform a leucine amber suppressor tRNA to serine identity. Eight changes are required. These are located in the acceptor stem and in the D stem.

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Identifiers

PMID: 1608979
DOI: 10.1073/pnas.89.12.5680
PMCID: PMC49356

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Source receipt: pubmed, retrieved 7 Sept 2026.

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