Article
tRNA anticodon shifts in eukaryotic genomes.
RNA (New York, N.Y.) - 1 Mar 2014
Rogers Hubert H, Griffiths-Jones Sam
Abstract excerpt
Embedded in the sequence of each transfer RNA are elements that promote specific interactions with its cognate aminoacyl tRNA-synthetase. Although many such "identity elements" are known, their detection is difficult since they rely on unique structural signatures and the combinatorial action of multiple elements spread throughout the tRNA molecule. Since the anticodon is often a major identity determinant...
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