Article
Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation.
BMC cancer - 5 Dec 2019
Le Puo-Hsien, Kuo Chia-Jung, Hsieh Yi-Chung, Chen Tsung-Hsing, Lin Chih-Lang, Yeh Chau-Ting, Liang Kung-Hao
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive solid tumor. HCC occurred at younger and elder ages were considered driven by different oncogenic mechanisms, and they demonstrated distinct clinical courses. METHODS: A total of 382 HCC patients treated by surgical resections was analyzed. RESULTS: A univariate-multivariate analysis showed that viral etiology (chronic hepatitis B, C) and the UDP...
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