Article
Association of tumor necrosis factor a-2 and a-8 microsatellite alleles with human papillomavirus and squamous intraepithelial lesions among women in Brazil.
Journal of clinical microbiology - 1 Aug 2005
Simões R T, Gonçalves M A G, Donadi E A, Simões A L, Bettini J S R, Duarte G, Quintana S M, Carvalho M W P, Soares E G
Abstract excerpt
Infection with oncogenic human papillomavirus (HPV) is considered to be the major risk factor for cervical cancer. Tumor necrosis factor (TNF) is a pluripotent cytokine that plays an important role in inhibiting the action of microbial agents, and TNF microsatellite polymorphisms have been associated with several diseases, including cancer and viral infections. This study analyzed the associations between TNFa to...
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