Article
Association of Polymorphisms in Cytokine genes with susceptibility to Precancerous Lesions and Cervical Cancer: A systematic review with meta-analysis.
Immunological investigations - 1 Jul 2021
de Moura Edilson Leite, Dos Santos Ana Caroline Melo, da Silva Denise Macedo, Dos Santos Bruna Brandão, Figueredo Diego de Siqueira, Moura Alexandre Wendell Araújo, da Silva Adriely Ferreira, Tanabe Ithallo Sathio Bessoni, de Lira Tanabe Eloiza Lopes, Lira Neto Abel Barbosa, Pereira E Silva Aline Cristine, de Carvalho Fraga Carlos Alberto, de Lima Filho José Luiz, de Farias Karol Fireman, Martins de Souza Elaine Virginia
Abstract excerpt
Objectives: This study investigated the relationship between single-nucleotide polymorphisms (SNPs) in cytokine genes and the susceptibility to Squamous Intraepithelial Lesions (SIL), cervical cancer and HPV infection through a systematic review with meta-analysis. To verify the effect of SNPs, we also analyzed the transcription factor binding affinity using bioinformatics tools.Methods: Seven electronic...
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