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Article

Solution structure of beta(2)-microglobulin and insights into fibrillogenesis.

Biochimica et biophysica acta - 10 Nov 2005

Esposito Gennaro, Corazza Alessandra, Viglino Paolo, Verdone Giuliana, Pettirossi Fabio, Fogolari Federico, Makek Ads, Giorgetti Sofia, Mangione Palma, Stoppini Monica, Bellotti Vittorio

Abstract excerpt

The solution structure of human beta(2)-microglobulin (beta(2)-m) was determined by (1)H NMR spectroscopy and restrained modeling calculations. Compared to the crystal structure of type I major histocompatibility complex (MHC-I), where the protein is associated to the heavy-chain component, several differences are observed, i.e., increased separation between strands A and B, displacements of strand C' and loop...

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Identifiers

PMID: 16081329
DOI: 10.1016/j.bbapap.2005.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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