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Article

Dynamics in the unfolded state of beta2-microglobulin studied by NMR.

Journal of molecular biology - 11 Feb 2005

Platt Geoffrey W, McParland Victoria J, Kalverda Arnout P, Homans Steve W, Radford Sheena E

Abstract excerpt

Many proteins form amyloid-like fibrils in vitro under conditions that favour the population of partially folded conformations or denatured state ensembles. Characterising the structural and dynamic properties of these states is crucial towards understanding the mechanisms of self-assembly in amyloidosis. The aggregation of beta2-microglobulin (beta2m) into amyloid fibrils in vivo occurs in the condition known as...

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Identifiers

PMID: 15663944
DOI: 10.1016/j.jmb.2004.11.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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