Article
Analysis of Aurora-A and hMPS1 mitotic kinases in mantle cell lymphoma.
International journal of cancer - 15 Jan 2006
Camacho Emma, Beà Silvia, Salaverría Itziar, López-Guillermo Armando, Puig Xavier, Benavente Yolanda, de Sanjosé Silvia, Campo Elias, Hernández Luis
Abstract excerpt
Aurora-A and hMPS1 are kinases involved in spindle checkpoint and centrosome duplication regulation and whose alterations have been associated with cell transformation and chromosome instability in different tumor models. In this study, we have examined the possible alterations of these genes in 58 mantle cell lymphomas (MCLs) and 4 MCL-related cell lines. Aurora-A was also examined in 46 diffuse large B-cell...
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