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Article

DNA damage checkpoints inhibit mitotic exit by two different mechanisms.

Molecular and cellular biology - 1 Jul 2007

Liang Fengshan, Wang Yanchang

Abstract excerpt

Cyclin-dependent kinase (CDK) governs cell cycle progression, and its kinase activity fluctuates during the cell cycle. Mitotic exit pathways are responsible for the inactivation of CDK after chromosome segregation by promoting the release of a nucleolus-sequestered phosphatase, Cdc14, which antagonizes CDK. In the budding yeast Saccharomyces cerevisiae, mitotic exit is controlled by the FEAR (for "Cdc-fourteen...

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Identifiers

PMID: 17485442
DOI: 10.1128/MCB.00095-07
PMCID: PMC1951953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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DNA damage checkpoints inhibit mitotic exit by two different mechanisms.PMID 17485442Read ↗

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