Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCK<sub>2</sub> receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours

20 Jul 2009

Abstract excerpt

The wild-type cholecystokinin type 2 (CCK(2)) receptor is expressed in many gastrointestinal and lung tumours. A splice variant of the CCK(2) receptor with retention of intron 4 (CCK(2)Ri4sv) showing constitutive activity associated with increased tumour growth was described in few colorectal, pancreatic and gastric cancers. Given the potential functional and clinical importance of this spliceoform, its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lung Cancer Research Studies
Share to Neuroendocrine Tumor Research Advances
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19627395
DOI: 10.1111/j.1582-4934.2009.00859.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

CCK<sub>2</sub> receptor splice variant with intron 4 retention in human gastrointestinal and lung tumoursPMID 19627395Read ↗

A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort.Semantic proximity Read ↗

CCK2 receptor expression transforms non-tumorigenic human NCM356 colonic epithelial cells into tumor forming cells.Semantic proximity Read ↗

Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes.Semantic proximity Read ↗

Characterization of the CCK-C (cancer) receptor in human pancreatic cancerSemantic proximity Read ↗

SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant.Semantic proximity Read ↗

Secretin receptor as a target in gastrointestinal cancer: expression analysis and ligand developmentSemantic proximity Read ↗

Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumoursSemantic proximity Read ↗

The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs.Semantic proximity Read ↗

Characterization of gastrin-releasing peptide receptors aberrantly expressed by non-antral gastric adenocarcinomas.Semantic proximity Read ↗

Abnormal processing of the human cholecystokinin receptor gene in association with gallstones and obesitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.