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Article

A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus.

Journal of medicinal chemistry - 11 Aug 2005

de Souza Noel J, Gupte Shrikant V, Deshpande Prasad K, Desai Vijaya N, Bhawsar Satish B, Yeole Ravindra D, Shukla Milind C, Strahilevitz Jacob, Hooper David C, Bozdogan Bülent, Appelbaum Peter C, Jacobs Michael R, Shetty Nitin, Patel Mahesh V, Jha Rasendrakumar, Khorakiwala Habil F

Abstract excerpt

There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive pathogens. The need may also be fulfilled by either exploring antibacterial agents having new mechanism of action or expanding known classes of antibacterial drugs. The paper describes a new chemical entity, compound 21, derived from hitherto little known...

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PMID: 16078842
DOI: 10.1021/jm050035f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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