Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Each protomer of a dimeric YidC functions as a single membrane insertase.

Scientific reports - 12 Jan 2018

Spann Dirk, Pross Eva, Chen Yuanyuan, Dalbey Ross E, Kuhn Andreas

Abstract excerpt

The membrane insertase YidC catalyzes the entrance of newly synthesized proteins into the lipid bilayer. As an integral membrane protein itself, YidC can be found as a monomer, a dimer or also as a member of the holotranslocase SecYEGDF-YajC-YidC. To investigate whether the dimeric YidC is functional and whether two copies cooperate to insert a single substrate, we constructed a fusion protein where two copies of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enzyme Stability
Share to Escherichia coli
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid Bilayers

Share to Membrane Transport Proteins

Share to Protein Conformation

Share to Protein Multimerization

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 29330366
DOI: 10.1038/s41598-017-18830-9
PMCID: PMC5766580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Each protomer of a dimeric YidC functions as a single membrane insertase.PMID 29330366Read ↗

Different regions of the nonconserved large periplasmic domain of Escherichia coli YidC are involved in the SecF interaction and membrane insertase activity.Semantic proximity Read ↗

Dynamic disulfide scanning of the membrane-inserting Pf3 coat protein reveals multiple YidC substrate contacts.Semantic proximity Read ↗

The conserved third transmembrane segment of YidC contacts nascent Escherichia coli inner membrane proteins.Semantic proximity Read ↗

Evolution of mitochondrial oxa proteins from bacterial YidC. Inherited and acquired functions of a conserved protein insertion machinery.Semantic proximity Read ↗

The Sec-independent function of Escherichia coli YidC is evolutionary-conserved and essential.Semantic proximity Read ↗

Involvement of SecDF and YidC in the membrane insertion of M13 procoat mutants.Semantic proximity Read ↗

Expression, purification and characterization of the Escherichia coli integral membrane protein YajC.Semantic proximity Read ↗

YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery.Semantic proximity Read ↗

Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function.Semantic proximity Read ↗

Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway.Semantic proximity Read ↗

Role of the Cytosolic Loop C2 and the C Terminus of YidC in Ribosome Binding and Insertion Activity.Semantic proximity Read ↗

Functional overlap but lack of complete cross-complementation of Streptococcus mutans and Escherichia coli YidC orthologs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.