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Article

Shh controls epithelial proliferation via independent pathways that converge on N-Myc.

Developmental cell - 1 Aug 2005

Mill Pleasantine, Mo Rong, Hu Ming Chang, Dagnino Lina, Rosenblum Norman D, Hui Chi-Chung

Abstract excerpt

Shh signaling induces proliferation of many cell types during development and disease, but how Gli transcription factors regulate these mitogenic responses remains unclear. By genetically altering levels of Gli activator and repressor functions in mice, we have demonstrated that both Gli function...

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Identifiers

PMID: 16054035
DOI: 10.1016/j.devcel.2005.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16054035-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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