Article
Methylenetetrahydrofolate reductase gene polymorphism is not related to the risk of ischemic cerebrovascular disease in a Brazilian population.
Clinics (Sao Paulo, Brazil) - 1 Jun 2007
Marie Suely Kazue Nagahashi, Shinjo Samuel Katsuyuki, Oba-Shinjo Sueli Mieko, da Silva Roseli, Barbosa Keila Cardoso, Yamamoto Fabio, Scaff Milberto
Abstract excerpt
PURPOSE: Data are conflicting concerning the risk for ischemic stroke associated with a common polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase C677T, which predisposes carriers to hyperhomocysteinemia. A meta-analysis study suggested that the 5,10-methylenetetrahydrofolate reductase 677TT genotype might have a small influence in determining susceptibility to ischemic stroke. METHODS: We...
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