Article
Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila.
Science (New York, N.Y.) - 29 Jul 2005
Aminetzach Yael T, Macpherson J Michael, Petrov Dmitri A
Abstract excerpt
To study adaptation, it is essential to identify multiple adaptive mutations and to characterize their molecular, phenotypic, selective, and ecological consequences. Here we describe a genomic screen for adaptive insertions of transposable elements in Drosophila. Using a pilot application of this screen, we have identified an adaptive transposable element insertion, which truncates a gene and apparently generates...
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