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Article

α-amanitin resistance in Drosophila melanogaster: A genome-wide association approach.

PloS one - 1 Jan 2017

Mitchell Chelsea L, Latuszek Catrina E, Vogel Kara R, Greenlund Ian M, Hobmeier Rebecca E, Ingram Olivia K, Dufek Shannon R, Pecore Jared L, Nip Felicia R, Johnson Zachary J, Ji Xiaohui, Wei Hairong, Gailing Oliver, Werner Thomas

Abstract excerpt

We investigated the mechanisms of mushroom toxin resistance in the Drosophila Genetic Reference Panel (DGRP) fly lines, using genome-wide association studies (GWAS). While Drosophila melanogaster avoids mushrooms in nature, some lines are surprisingly resistant to α-amanitin-a toxin found solely in mushrooms. This resistance may represent a pre-adaptation, which might enable this species to invade the mushroom...

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Identifiers

PMID: 28241077
DOI: 10.1371/journal.pone.0173162
PMCID: PMC5328632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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