Article
Glutathione S-transferase T1 polymorphisms are associated with outcome in colorectal cancer.
Carcinogenesis - 1 Dec 2005
Rajagopal R, Deakin M, Fawole A S, Elder J B, Elder J, Smith V, Strange R C, Fryer A A
Abstract excerpt
Colorectal cancer (CRC) remains a significant cause of mortality accounting for approximately 10% of all deaths from malignancy in the western world. Polymorphism in the glutathione S-transferase GSTT1 gene has been associated with CRC risk in some but not all studies. In this study, we examined associations between GSTT1 genotypes and CRC risk, and prognosis in 361 cases and 881 unrelated controls. GSTT1 null...
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