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Article

Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma.

International journal of cancer - 20 Apr 1999

Zhang H, Ahmadi A, Arbman G, Zdolsek J, Carstensen J, Nordenskjöld B, Söderkvist P, Sun X F

Abstract excerpt

Gene codings for glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) are polymorphic in humans with null genotypes present in approximately 20 and 50%, respectively. A significant excess of homozygous null GSTT1 and GSTM1 genotypes has been demonstrated among individuals with certain types of cancers. This finding suggests that GSTT1 and GSTM1 may play a role in tumour susceptibility. However, reports concerning...

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Source

Identifiers

PMID: 10096244
DOI: 10.1002/(sici)1097-0215(19990420)84:2<135::aid-ijc7>3.0.co;2-c

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma.PMID 10096244Read ↗

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Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma.Semantic proximity Read ↗

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Glutathione S-transferase M1, T1, P1 genotypes and risk for development of colorectal cancer.Semantic proximity Read ↗

Association between glutathione S-transferase T1, M1, and P1 genotypes and the risk of colorectal cancer.Semantic proximity Read ↗

Evaluation of deletion polymorphisms of glutathione S-transferase genes and colorectal cancer risk in ethnic Kashmiri population: A case-control study.Semantic proximity Read ↗

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