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Article

GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis.

European journal of cancer (Oxford, England : 1990) - 1 Jun 2010

Economopoulos Konstantinos P, Sergentanis Theodoros N

Abstract excerpt

Glutathione S-transferases (GSTs) catalyse reactions between glutathione and lipophilic compounds with electrophilic centres, leading to neutralisation of toxic compounds, xenobiotics and products of oxidative stress. Controversy exists about whether GST polymorphisms (GSTM1 null/present genotype, GSTT1 null/present genotype, GSTP1 Ile105Val and GSTA1 *A/*B) represent risk factors for colorectal cancer. This...

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Source

Identifiers

PMID: 20207535
DOI: 10.1016/j.ejca.2010.02.009

Genes

GSTM1
GSTT1
GSTA1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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