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Article

Glutathione S-transferase M1 and T1 polymorphisms: susceptibility to colon cancer and age of onset.

Carcinogenesis - 1 Jul 1995

Chenevix-Trench G, Young J, Coggan M, Board P

Abstract excerpt

The M1 member of the Mu subclass of glutathione S-transferase (GSTM1) is only expressed in about 50% of individuals. In contrast, GSTT1, a member of the theta class which has been recently shown to be polymorphic, is expressed in 85% of Australian individuals. Previous studies have shown a significant excess of homozygous null GSTM1 genotypes among individuals with colorectal cancer, particularly those with...

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Source

Identifiers

PMID: 7614702
DOI: 10.1093/carcin/16.7.1655

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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