Article
Prediction of BRCA1/2 mutation status in patients with ovarian cancer from a hospital-based cohort.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Mar 2007
Jacobi Catharina E, van Ierland Yvette, van Asperen Christi J, Hallensleben Eric, Devilee Peter, Jan Fleuren Gert, Kenter Gemma G
Abstract excerpt
PURPOSE: To describe patient, tumor, and family histories of cancer in a hospital-based cohort of patients with ovarian cancer and to identify the predictive value of these characteristics for (non)carrying a BRCA1 or BRCA2 mutation. METHODS: Women diagnosed with invasive ovarian cancer between 1999 and 2003 in the west region of The Netherlands and unselected for age at diagnosis or cancer family history were...
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