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Article

VEGF -460 genotype plays an important role in progression to chronic kidney disease stage 5.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2005

Summers Angela M, Coupes Beatrice M, Brennan Mary Frances, Ralph Shirley A, Short Colin D, Brenchley Paul E C

Abstract excerpt

BACKGROUND: Changes in renal vasculature, with vascular and interstitial fibrosis, are hallmarks of progression to chronic kidney disease (CKD) stage 5. Vascular endothelial growth factor (VEGF) is a potent angiogenic and vascular permeability factor. Transforming growth factor-beta1 (TGF-beta1) plays a critical role in promoting extracellular matrix (ECM) deposition and fibrosis. This study investigates whether...

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PMID: 16046504
DOI: 10.1093/ndt/gfi029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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