Article
The GA genotype of the -1154 G/A (rs1570360) vascular endothelial growth factor (VEGF) is protective against hypertension-related chronic kidney disease incidence.
Molecular and cellular biochemistry - 1 Jul 2016
Małkiewicz Anna, Słomiński Bartosz, Skrzypkowska Maria, Siebert Janusz, Gutknecht Piotr, Myśliwska Jolanta
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a highly specific mitogen with angiogenic and vascular permeability activities for endothelial cells. VEGF participates in maintaining the renal vasculature integrity. There is no doubt that hypertension accelerates progression to renal dysfunction, resulting in chronic kidney disease (CKD). The purpose of our study was to examine the VEGF -1154 G/A (rs1570360)...
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