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Monte Carlo Simulation of Base and Nucleotide Excision Repair of Clustered DNA Damage Sites. II. Comparisons of Model Predictions to Measured Data

1 Aug 2005

Abstract excerpt

Clustered damage sites other than double-strand breaks (DSBs) have the potential to contribute to deleterious effects of ionizing radiation, such as cell killing and mutagenesis. In the companion article (Semenenko et al., Radiat. Res. 164, 180-193, 2005), a general Monte Carlo framework to simulate key steps in the base and nucleotide excision repair of DNA damage other than DSBs is proposed. In this article,...

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PMID: 16038590
DOI: 10.1667/rr3414

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