Article
Genomic search for prostate cancer predisposition loci in Utah pedigrees.
The Prostate - 1 Dec 2005
Camp Nicola J, Farnham James M, Cannon Albright Lisa A
Abstract excerpt
BACKGROUND: We report a genome linkage scan in extended Utah pedigrees, utilizing a pedigree-splitting approach to reduce intra-familial heterogeneity. METHODS: Fifty-nine pedigrees with at least four Prostate cancer (PrCa) cases and no more than two meioses separating PrCa cases were analyzed using the CIDR genomic search STRP marker set. Parametric linkage analyses using dominant and recessive models were...
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