Article
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
The Journal of general virology - 1 Aug 2005
Scott G M, Ng H-L, Morton C J, Parker M W, Rawlinson W D
Abstract excerpt
Human cytomegalovirus (HCMV) resistance to antivirals is a significant clinical problem. Murine cytomegalovirus (MCMV) infection of mice is a well-described animal model for in vivo studies of CMV pathogenesis, although the mechanisms of MCMV antiviral susceptibility need elucidation. Mutants resistant to nucleoside analogues aciclovir, adefovir, cidofovir, ganciclovir, penciclovir and valaciclovir, and the...
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