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Article

Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Apr 2002

Gilbert Christian, Bestman-Smith Julie, Boivin Guy

Abstract excerpt

Nucleoside analogues such as acyclovir and ganciclovir have been the mainstay of therapy for alphaherpesviruses (herpes simplex virus (HSV) and varicella-zoster virus (VZV)) and cytomegalovirus (CMV) infections, respectively. Drug-resistant herpesviruses are found relatively frequently in the clinic, almost exclusively among severely immunocompromised patients receiving prolonged antiviral therapy. For instance,...

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Share to Cytomegalovirus and herpesvirus research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Viral

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Source

Identifiers

PMID: 12135584
DOI: 10.1016/s1368-7646(02)00021-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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