Article
Analysis of single nucleotide polymorphisms in the promoter region of interleukin-10 by denaturing high-performance liquid chromatography.
Journal of biomolecular techniques : JBT - 1 Jun 2005
Guzowski Dorothy, Chandrasekaran Alamelu, Gawel Craig, Palma Jacqueline, Koenig Jonathan, Wang Xue Ping, Dosik Michael, Kaplan Mark, Chu Charles C, Chavan Sangeeta, Furie Richard, Albesiano Emilia, Chiorazzi Nicholas, Goodwin Leslie
Abstract excerpt
Interleukin-10 (IL10), an anti-inflammatory cytokine, has been implicated in a variety of immune- and inflammatory-related diseases. We investigated the following SNPs: -1082, -819, -592 in the promoter region of IL10 in a normal (control) population and selected diseases: breast cancer (BrCa), systemic lupus erythematosus (SLE), and B-cell chronic lymphocytic leukemia (B-CLL) by denaturing high-performance...
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