[Congenic rats for hypertension studies].

Abstract excerpt

A congenic rat has a small genomic fragment transferred from a donor strain into a recipient strain. It is therefore possible to make a hypertensive congenic strain with a single unknown hypertensive gene originating from a genetic hypertensive model rat such as SHR. Such a congenic strain is useful in the search for hypertension genes in rats. It can be applied (1) to further dissection of QTL regions, (2) to...

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