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Article

New mutations in the APC gene in familial adenomatous polyposis: detection, characterization, and analysis.

Bulletin of experimental biology and medicine - 1 Mar 2005

Muzaffarova T A, Pospekhova N I, Sachkov I Yu, Kuz'minov A M, Ginter E K, Karpukhin A V

Abstract excerpt

The spectrum of mutations in the APC gene in familial adenomatous polyposis was detected in a sampling from the Russian population. Fifteen new mutations were found. Deletions associated with the loss of only 1 or 2 nucleotides (89% cases) prevailed among new (unique) mutations, while all known deletions were caused by the loss of 4 or 5 nucleotides. The detected differences in the deletion characteristics...

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Share to Adenomatous Polyposis Coli
Share to Codon, Terminator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genes, APC

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Share to Mutation, Missense

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Source

Identifiers

PMID: 16027851
DOI: 10.1007/s10517-005-0292-4

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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