Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APC mutation spectrum of Norwegian familial adenomatous polyposis families: high ratio of novel mutations.

Journal of cancer research and clinical oncology - 1 Oct 2009

Andresen Per Arne, Heimdal Ketil, Aaberg Kristin, Eklo Katrine, Eklo Kristin, Ariansen Sarah, Silye Alexandra, Fausa Olav, Aabakken Lars, Aretz Stefan, Eide Tor J, Gedde-Dahl Tobias

Abstract excerpt

INTRODUCTION: Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited disease caused by mutations in the adenomatous polyposis coli (APC) gene. Massive formation of colorectal adenomas, of which some will inevitably develop into adenocarcinomas, is the hallmark of the disease. Characterization of causative APC mutations allows presymptomatic diagnosis, close follow-up and prophylactic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Adenoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenomatous Polyposis Coli

Share to Adenomatous Polyposis Coli Protein

Share to Chromatography, High Pressure Liquid

Share to Family

Share to Germ-Line Mutation

Share to Norway

Source

Identifiers

PMID: 19444466
DOI: 10.1007/s00432-009-0594-4

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APC mutation spectrum of Norwegian familial adenomatous polyposis families: high ratio of novel mutations.PMID 19444466Read ↗

Clinical characterization and the mutation spectrum in Swedish adenomatous polyposis families.Semantic proximity Read ↗

Novel APC mutations in Czech and Slovak FAP families: clinical and genetic aspects.Semantic proximity Read ↗

An update of the variant spectrum of the APC gene in Iranian familial adenomatous polyposis patients.Semantic proximity Read ↗

Detecting APC Gene Mutations in Familial Adenomatous Polyposis (FAP).Semantic proximity Read ↗

Novel and reported APC germline mutations in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

Mutation Spectrum of Familial Adenomatous Polyposis Patients in Turkish Population: Identification of 3 Novel APC Mutations.Semantic proximity Read ↗

Genetic differences in familial adenomatous polyposis syndrome in a Hungarian population: A prospective single center study.Semantic proximity Read ↗

[Genetic analysis in familial adenomatous polyposis].Semantic proximity Read ↗

The mutation spectrum of the APC gene in FAP patients from southern Italy: detection of known and four novel mutations.Semantic proximity Read ↗

Mutational screening through comprehensive bioinformatics analysis to detect novel germline mutations in the APC gene in patients with familial adenomatous polyposis (FAP).Semantic proximity Read ↗

Mutational spectrum of APC and genotype-phenotype correlations in Greek FAP patients.Semantic proximity Read ↗

Germline APC mutation spectrum derived from 863 genomic variations identified through a 15-year medical genetics service to French patients with FAP.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.