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Article

Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.

Bone - 1 Oct 2005

Hishiya Akinori, Ito Masako, Aburatani Hiroyuki, Motoyama Noboru, Ikeda Kyoji, Watanabe Ken

Abstract excerpt

ATM is a member of the PI-3 kinase protein family, encoded by the gene, ATM, responsible for ataxia telangiectasia (AT). AT is recognized as a genomic instability syndrome, sharing accelerated senescence symptoms in human and mouse. Here, we present evidence that the bone phenotype of Atm knockou...

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Source

Identifiers

PMID: 16027059
DOI: 10.1016/j.bone.2005.05.012

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16027059-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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