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Article

Poly (ADP-ribose) polymerase-1 haplotypes are associated with coeliac disease.

International journal of immunogenetics - 1 Aug 2005

Rueda B, Koeleman B P C, López-Nevot M A, Ortega E, Maldonado J, López M, Polanco I, Martín J

Abstract excerpt

In coeliac disease (CD) there is an inflammatory status of the intestinal mucosa because of a high expression of proinflammatory mediators. The nuclear protein poly (ADP-ribose) polymerase-1 (PARP-1) has been implicated in the initial inflammatory response by modulating transcription of inflammation-related genes. The aim of this work was to investigate the role of PARP-1 gene promoter region haplotypes in...

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Identifiers

PMID: 16026592
DOI: 10.1111/j.1744-313X.2005.00521.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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